MIRACLES

Blood plasma is the liquid component of blood that holds proteins, hormones, and nutrients in suspension. Derivatives are specific proteins isolated from plasma through a process called fractionation.

Key Derivatives and Their Functions

• Albumin: Used to treat volume loss in trauma or surgery and to manage liver failure.

• Immunoglobulins (IVIG): Essential for patients with primary immunodeficiency or autoimmune neurological disorders.

• Coagulation Factors: Crucial for managing Hemophilia A and B, allowing for effective blood clotting.

The Fractionation Process

Plasma is subjected to varying temperatures and chemical environments (Cohn process) to precipitate specific proteins. This ensures that the final product is highly concentrated and free of viral contaminants.